Lab disinfectant harms mouse fertility
Two chemicals widely used in cleaning agents for homes, offices and hospitals cause birth defects and fertility problems in mice whose cages have been in contact with them, according to Patricia Hunt at Washington State University in Pullman. The quaternary ammonium compounds ADBAC (n-alkyl dimethyl benzyl ammonium chloride) and DDAC (didecyl dimethyl ammonium chloride) were identified after an exhaustive search for what was causing a massive drop-off in mouse fertility after Hunt moved her research animals to Pullman from Case Western Reserve Medical School in Cleveland, Ohio, in 2005.