Development of a simple noninvasive model to predict significant fibrosis in patients with chronic Hepatitis B: Combination of ultrasound elastography, serum biomarkers, and individual characteristics
The accurate assessment of liver fibrosis is clinically important in patients with chronic hepatitis B (CHB). Blood tests and elastography are now widely used for the noninvasive diagnosis of liver fibrosis in CHB patients. The aim of this study was to develop a new and more accurate predictive model, which combines elastography data, serum biomarkers, and individual characteristics, to discriminate between CHB patients with and without significant liver fibrosis.