Biomolecular markers within the core axis of aging and particulate air pollution exposure in the elderly: A cross-sectional study
Telomere length and mitochondrial DNA (mtDNA) content are markers of aging and aging-related diseases. There is inconclusive evidence concerning the mechanistic effects of airborne particulate matter (PM) exposure on biomolecular markers of ageing. The present study examines the association between short- and long-term PM exposure with telomere length and mtDNA content in elderly and investigates to what extend this association is mediated by expression of genes playing a role in the telomere-mitochondrial axis of aging.