A randomized, placebo-controlled trial of the bivalent killed, whole-cell, oral cholera vaccine in adults & children in Kolkata

An effective vaccine against cholera has been used for public health purposes in Vietnam since the 1990s. This vaccine was reformulated to meet WHO requirements. The researchers assessed the safety and immunogenicity of the reformulated bivalent (Vibrio cholerae 01 and 0139) killed whole cell oral vaccine in a cholera endemic area in Kolkata, India.